Resume of Cunduo Tang
Name: Cunduo Tang
Sex: Male
Title: Associate Professor
E-mail: tcd530@126.com
Honorary Titles: Scientific and technological innovation talents in universities of Henan Province, Young scientists in Henan province
1. EDUCATION
2008.09-2014.01, Jiangnan University, fermentation engineering, doctorate
2004.09-2008.06, Suzhou University of Science and Technology, biotechnology, bachelor
2. PROFESSIONAL EXPERIENCE
2024.05-present, College of Life Sciences, Nanyang Normal University, Associate Professor
2020.10-2024.04, College of Life Sciences and Agricultural Engineering, Nanyang Normal University, Associate Professor
2015.09-2020.09, College of Agricultural Engineering, Nanyang Normal University, Lecturer
2014.02-2015.08, College of Life Sciences and Technology, Nanyang Normal University, Lecturer
3. COURSES
For undergraduate courses have genetic engineering, enzyme engineering, protein technology and principles of fermentation technology.
For graduate courses have enzyme engineering and principles of fermentation technology
4. RESEARCH
(1). AI-assisted rational design and modification of proteins;
(2). Biosynthesis of functional food and drug intermediates;
(3). Artificial capture and storage of carbon dioxide and high-value utilization
5. PUBLICATIONS
(1). Shi Hongling, Fu Muran, Yuan Shuwei, Lu Yunfeng, Yang Zhuan, Yue Chao, Yao Lunguang*, Xue Chuang*, Tang Cunduo*. Engineered Escherichia coli Whole Cell-Mediated Electro-Biocatalysis for Carbon Dioxide to Formic Acid Conversion. ACS Sustainable Chem. Eng. 2024, 12 (14): 5544-5554. (JCR Q1)
(2). Hu Die, Jia Xue-Wei, Lu Jia-Lan, Lu Zhi-Yi, Tang Cunduo*, Xue Feng, Huang Chao, Ren Qing-Gong, He Yu-Cai*. Chemoenzymatic Asymmetric Synthesis of Chiral Triazole Fungicide (R)-Tebuconazole in High Optical Purity Mediated by an Epoxide Hydrolase from Rhodotorula paludigensis. J Agric Food Chem 2024, 72 (18): 10428-10438. (JCR Q1)
(3). Zhang Xiang, Zhang Xichuan, Shi Hongling, Zhang Huimin, Zhang Jianhui, Yue Chao, Li Dandan*, Yao Lunguang*, Tang Cunduo*. Combining Flexible Region Design and Automatic Design to Enhance the Thermal Stability and Catalytic Efficiency of Leucine Dehydrogenase. J Agric Food Chem 2024, 72 (24): 13801-13811. (JCR Q1)
(4). Tang Cunduo*, Li Xiang, Shi Hong-Ling, Jia Yuan-Yuan, Dong Zi-Xing, Jiao Zhu-Jin, Wang Lin-Feng, Xu Jian-He, Yao Lun-Guang*, Kan Yun-Chao*. Efficient expression of novel glutamate decarboxylases and high level production of gamma-aminobutyric acid catalyzed by engineered Escherichia coli. Int J Biol Macromol 2020, 160: 372-379. (JCR Q1)
(5). Tang Cunduo*, Ding Peng-Ju, Shi Hong-Ling, Jia Yuan-Yuan, Zhou Mao-Zhi, Yu Hui-Lei, Xu Jian-He, Yao Lun-Guang*, Kan Yun-Chao*. One-Pot Synthesis of Phenylglyoxylic Acid from Racemic Mandelic Acids via Cascade Biocatalysis. J Agric Food Chem 2019, 67 (10): 2946-2953. (JCR Q1)
(6). Tang Cun-Duo*, Shi Hong-Ling, Xu Jian-He, Jiao Zhu-Jin, Liu Feng, Ding Peng-Ju, Shi Hong-Fei, Yao Lun-Guang,Kan Yun-Chao. Biosynthesis of Phenylglyoxylic Acid by LhDMDH, a Novel D-Mandelate Dehydrogenase with High Catalytic Activity. J Agric Food Chem 2018, 66 (11): 2805-2811. (JCR Q1)
(7). Liu Xin-Xin, Wang Yao, Zhang Jian-Hui, Lu Yun-Feng, Dong Zi-Xing, Yue Chao, Huang Xian-Qing, Zhang Si-Pu, Li Dan-Dan, Yao Lun-Guang, Tang Cun-Duo*. Engineering Escherichia coli for high-yielding 2,5-Dimethylpyrazine synthesis from L-Threonine by reconstructing metabolic pathways and enhancing cofactors regeneration. Biotechnology for Biofuels and Bioproducts 2024, 17 (1): 44. (JCR Q2)
(8). Zhang Xiang, Zhang Xi-Chuan, Shi Hong-Ling, Zhang Hui-Min, Zhang Jian-Hui, Kan Yun-Chao, Li Dan-Dan, Yao Lun-Guang, Tang Cun-Duo*. Enhancing the thermostability of the leucine dehydrogenase from Planifilum fimeticola through rational design of the flexible region. Molecular Catalysis 2024, 559: 114048. (JCR Q2)
(9). Liu Xin-Xin, Xi Xiao-Qi, Shen Tai-Song, Shi Hong-Ling, Zhang Ying-Jun, Kan Yun-Chao, Yao Lun-Guang, Tang Cun-Duo*. Enhancing biosynthesis efficiency of 2,5-dimethylpyrazine by overexpressing -threonine dehydrogenase and NADH oxidase in Escherichia coli. Molecular Catalysis 2023, 550: 113550. (JCR Q2)
(10). Yuan Shu-Wei, Fu Mu-Ran, Xian Yi-Meng, Shi Hong-Ling, Chun Chang, Yao Lun-Guang, Tang Cun-Duo*, Chen Chang-Po. Efficient heterologous expression of formate dehydrogenase and preliminary determination of the potential for conversion of carbon dioxide to formate. Molecular Catalysis 2023, 548: 113455. (JCR Q2)
(11). Tang Cun-Duo*, Zhang Xiang, Shi Hong-Ling, Liu Xin-Xin, Wang Hong-Yan, Lu Yun-Feng, Zhang Si-Pu, Kan Yun-Chao,Yao Lun-Guang. Improving catalytic activity of Lactobacillus harbinensis -mandelate dehydrogenase toward -o-chloromandelic acid by laboratory evolution. Molecular Catalysis 2022, 531: 112700. (JCR Q2)
(12). Tang Cun-Duo, Zhang Zhen-Hua, Shi Hong-Ling, Xie Yu-Li, Yang Tian-Tian, Lu Yun-Feng, Zhang Si-Pu, Bai Fang-Hui, Kan Yun-Chao,Yao Lun-Guang. Directed evolution of formate dehydrogenase and its application in the biosynthesis of L-phenylglycine from phenylglyoxylic acid. Molecular Catalysis 2021, 513: 111666. (JCR Q2)
6. PATENTS
(1). Tang Cun-Duo, Shi Hong-Ling, Kan Yun-Chao, et al. A D-mandelate dehydrogenase, gene, genetically engineered bacterium and its application, 2019-09-24, China National invention patent, ZL201710969932.0.
(2). Tang Cun-Duo, Yao Lun-Guang, Kan Yun-Chao, et al. The invention relates to a gene encoding glutamate decarboxylase LsGAD, a recombinant engineering bacterium and a kombucha fermentation bacterium, 2023-03-24, China National invention patent, ZL201911234346.7