Yanhua Wang, Ph.D.

Associate professor

Research Natural Product Research and Development

College of Life Sciences,

Nanyang Normal University, China Nanyang, Henan Province 473061 China

Tel: 86-377-63513726 (O)

86-15938829202 (M)

Email: nywyhua@hotmail.com; 15938829202@163.com

Education

2005.09 – 2009.06 Ph.D. degree, major in Biomedical Engineering, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, China. Thesis：The impact of normal shear stress on migration of endothelial cell cocultured with smooth muscle cells.

2001.09 – 2004.06 Master degree, major in Biochemistry and Molecular Biology, College of Crop Science, Fujian Agriculture and Forest University, China.

1997.09 – 2001.06 Bachelor degree，major in Life Science，College of Biology, Henan University, China

Professional Experiences

2017.12-2019.01 Visiting Scholar, Duke University, North Carolina, American

2015.06-Present Associate Professor of Biology, Normal University of China, Nanyang, Henan, China 2012.09-Present Supervisor of Biology Engineering Master Degree, Normal University of China, Nanyang,

Henan, China

2010.01-Present Principal Investigator-Wolong Scholar, Nanyang Normal University of China, Nanyang, Henan, China

2007.06-2015.06 Lecture of Biology, Nanyang Normal University of China, Nanyang, Henan, China

Awards and Honors

2014 Best Individual Award in Nanyang Normal University

2014 Excellent Teacher in Nanyang Normal University

2014 Second Award in Nanyang Normal University teaching competition

2013 Second Award in Nanyang Normal University bilingual teaching competition 2013 Best design Award in Nanyang Normal University multimedia course competition 2012 Academic Leader of Nanyang City

2012 Best Paper Award in Science and Technology of Henan Province Education Department 2012 Wolong Scholar of Nanyang Normal University

2008 Best Paper Award in China National Doctoral Thesis Conference

Professional Society Memberships

2009-present Member of council, Henan Biophysical Society 2015-Present Editor Board Member of Food Science Journal

2012-Present Member of Fu-Niu Mountain Insect Biology Laboratory

2011-Present Member of Agricultural Biomass Resource Engineering Center 2010-Present Member of Insect Bioreactor of Henan Engineering Laboratory

Research Grants

2012-2016 National Natural Science Foundation of China, Title:  Study  on  the  Mechanism  of  the  Regulation of Vascular Endothelial Function by Shear Stress Based on Metabolic Network (No.11102092, Principal Investigator).

2008-2012 National Natural Science Foundation of China, Title: Mechanism and mechanism of vascular migration and differentiation (No. 10732070, Participator).

2008-2010 National Natural Science Foundation of China, Title: Flow  shear  stress  spatial  gradient  regulation of vascular smooth muscle cell migration and the role of signal communication between cells (No. 10772120, Participator).

2006-2008 National Natural Science  Foundation  of  China,  Title:  Migration  and  Cytoskeleton  of Endothelial Cells Cultured in Vascular Smooth Muscle Cells under Shear Stress (No. 10572096, Participator).

Peer-Reviewed Journal Publications (*Corresponding Author)

1. Wang Yan-Hua, Yue Yaoli, Wu Fuhua et al. Study on the optimization of peperin extraction from black pepper. Basic&Clinical Phamarcology & Toxicology, 2021,128:219-221.( SCI 3 区)

2. Yanhua Wang; Chun-Chi Chang; Liangli Wang; Fan Yuan ; Enhancing Cell Viability and

Efficiency of Plasmid DNA Electrotransfer Through  Reducing Plasma Membrane Permeabilization.

Bioelectricity, 2020, 2(3): 251-257 (期刊论文

3. Wang Yan-Hua, Yan Zhi-Qiang, Shen Bao-Rong, Cheng Bin-bin, Zhao Dan, Wang Xiao-Dong, and Jiang Zong-Lai*. Normal shear stress protects against migration of endothelial cells co-cultured with

vascular smooth muscle cells. Ann Biomed Eng, 2010; 38(3):729-737.

4. Wang Yan-Hua, Yan Zhi-Qiang, Shen Bao-Rong, Zhang Lu, Zhang Ping and Jiang Zong-Lai*. Vascular smooth muscle cells promote endothelial cell adhesion via microtubule dynamics and activation of paxillin and ERK pathway in a co-culture system. Eur J Cell Biol, 2009; 88(11): 701-709.

5. Wang Han-qin. Bai Ling ， Wang Yan-hua, Jiang Zong-lai* ． Shear stress-induced regulation of vascular smooth muscle cells adhesion in a co-culture system with endothelial cells. J Med Biomech, 2007; 22(1):4-7.

6. Cao Ye, Bai Ling, Yan Zhi-Qiang, Wang Yan-Hua, Jiang Zong-Lai*. Shear stress and vascular smooth muscle cells promote endothelial differentiation of endothelial progenitor cells via activation of Akt. Clin Biomech, 2008; 23:S118–S124.

7. Cao Ye, Yan Zhi-Qiang, Bai Ling, Wang Yan-Hua, Shen Bao-rong, Jiang Zong-Lai*. The effect of vascular smooth muscle cells on the adhesion, proliferation and morphology  of  endothelial progenitor cells in a co-culture system. Chinese J Clin Anat, 2008;21(1):69-72.

8. Huang Lang-xian, Bai Ling, Wang Han-qing, Cao Ye, Wang Yan-hua, Jiang Zong-lai*. Flow-mediated regulation of endothelial cell microtubule cytoskeleton in a co-culture system. J Med Biomech, 2006; 21(4):254-258.

9. Wang Yan-Hua*, Wu Fu-hua, Guo Zhao-han, Peng Mingxing, Xia Min, Peng Zhen-ling, Wang Xiao-li, Liang Zi-an, Zhang Nai-qun. Analysis Fatty Acids Profile in Tabanus bivittatus Mats with Gas Chromatography-Mass Spectrometry. Open Biotechn J, 2015; 9:113-118.

10. Wang Yan-Hua*,Wu Fu-hua, Guo Zhao-han, Peng Mingxing, Zhang yan-nan, Peng Zhen-ling, Du Min-hua, Zhang Cai-ying, Liang Zi-an. Optimization of Extraction Process for Polysaccharide in Salvia Miltiorrhiza Bunge Using Response Surface Methodology. Open Biomed Eng J, 2015; 9:347-350.

11. Wang Yan-Hua*, Wu Fu-hua, Guo Zhao-han, Peng Ming-xing, Song Wan-hua. Optimization of Ultrasonic-Assisted Extraction and Antioxidant Activities of Polysaccharides from the Roots  of Salvia miltiorrhiza Bge. Food Sci, 2015; 36(18):7-12.

12. Wang Yan-Hua*, Wu Fu-hua, Jiang Zong-lai. Force - vascular metabolomics and cardiovascular disease. Acta Biophys Sin, 2013; 29(10): 751-758.

13. Wang Yan-Hua*, Wu Fu-hua, Huang Si-liang, Wang Xiao-li, Xia Min. The impact and modulation mechanism of normal shear stress on migration of endotheial cell. Chem Life, 2013; 33(1): 1-5.

14. Wang Yan-Hua*, Wu Fu-hua Yang Jian-wei. The research on blended learning model of cell biology under network. J Nanyang Normal University, 2012; 11(6):106-108.

15. Wang Yan-Hua*, Wu Fu-hua Yang Jian-wei. Extraction and Stability of  Sunscreen Constituents from Cornus of ficinalis. Chinese J Spectroscopy Lab, 2012; 29 (4): 2241-2242.

16. Wang Yan-Hua*, Wu Fu-hua, Du Min-hua, Wang Xiao-li. Screening of natural sunscreen effect of Chinese herbal medicine research. Lishizhen Med Materia Med Res, 2013; 24(2): 263-264.

17. Zhang Shu*, Wang Yan-Hua, Ｇ uo Bao-dang, Ji Jun, Li Huifang, Hu Xiao-min, Yao Lun-guang. Studies on the Expressions of Chicken Thymosin β ４ and β15 in E.coli and Their Biologicl Activities. J Henan Agricultural Sci, 2014; 43(12):140-143.

18. Ding Cheng-hua ， Cao Feng-pu, Wang Yan-Hua*. Extraction of Fatty Constituents from Tabanus bivittatus and Their Analysis by GC-MS. J Chinese Med Materials, 2013; 36(2): 188-190.

19. Guo Zhao-han, Li Yin-he, Peng Ming-xing, Huang Ran-tao, Wang Yan-Hua*. Optimization for