董自星

作者:办公室主任

姓 名:董自星

性 别:男

职 称:讲师

所在系别:生命科学与农业工程学院

电子邮箱:star1987.com@163.com

个人简历

2019.04—现在:南阳师范学院生命科学与农业工程学院,从事教学科研工作

2015.06—2019.03:天津科技大学化工与材料学院,从事教学科研工作

2014.11—2015.05:天津科技大学生物工程学院,从事教学科研工作
2008.09—2014.01:江南大学发酵工程系,获工学博士学位
2004.09—2008.07:东北农业大学生物工程系,获工学学士学位

教学工作

主讲课程《蛋白质组学》、《发酵工艺学》和《专业英语》;

研究方向

生物催化与生物转化

科研成果

课题项目:
1.农业生物质综合生物加工用酶库、酶复配技术与新菌种(2019-2021),国家重点研发计划项目(政府间国际科技创新合作重点专项,参与,在研;

2.基于末端组学深度解析食品碱性蛋白酶的动态水解规律及其位点选择特性(2019-2022),国家自然科学基金面上项目,参与,在研;

3.维生素D3前体生物合成关键酶胆固醇7-脱氢酶系的构效研究(2018-2021),国家自然科学基金面上项目,参与,在研;

4.酶与生物催化关键技术(2018-2020),天津市高等学校创新团队建设计划项目,参与,已结题;

5.阿胶酶解技术及其专用酶(2016-2017),东阿阿胶股份有限公司技术开发项目,参与,已结题;

6.脱枝酶生产技术和菌种(2017-2018),山东隆科特酶制剂有限公司技术开发项目,参与,已结题;

7.交替糖蔗糖酶的产物特异性改造(2016-2018),天津科技大学青年教师创新基金(科研类理工组),主持,已结题;

8.耐热脂肪酶产生菌的筛选及其发酵优化研究(2014-2015),天津市科委人才引进与科技合作项目,参与,已结题。

论文著作:

1、Zixing Dong*, Shuangshuang Yang, Byonghoon Lee. Bioinformatic mapping of a more precise Aspergillus niger degradome [J]. Sci Rep-UK, 2021, 11(1): 693.

2、Zixing Dong*, Cunduo Tang, Yunfeng Lu, Lunguang Yao, Yunchao Kan. Microbial oligo-α-1,6-glucosidase: Current developments and future perspectives [J]. Starch - Stärke, 2020, 72(1-2): 1900172.

3、Zixing Dong*, Xiaoling Chen, Ke Cai, Peili Shen, Kangming Tian, Peng Jin, Xiaoguang Liu, Zhengxiang Wang*. Overexpression of the Bacillus licheniformis GroES enhances thermotolerance of Bacillus subtilis WB600 [J]. Biotechnol Biotec Eq, 2018, 32 (6): 1527-1532.

4、Zixing Dong*, Beyonghoon Lee. Bile salt hydrolases: Structure and function, substrate preference and inhibitor development [J]. Protein Sci, 2018, 27: 1742-1754.

5、Zixing Dong, Xiaoling Chen, Ke Cai, Zhixin Chen, Hongbin Wang, Peng Jin, Xiaoguang Liu, Kugenthiren Permaul, Suren Singh, Zhengxiang Wang*. Exploring the metabolic responses of Bacillus licheniformis to temperature stress by gas chromatography/mass spectrometry [J]. J Microbiol Biotechnol, 2018, 28(3): 473-481.

6、Haiyang Wu, Xiaojing Tian, Zixing Dong*, Yongjie Zhang, Lei Huang, Xiaoguang Liu, Peng Jin, Fuping Lu, Zhengxiang Wang*. Engineering of Bacillus amyloliquefaciens α-amylase with improved calcium independence and catalytic efficiency by error-prone PCR [J]. Starch - Stärke, 2018, 70(3-4): 1700175.

7、Zixing Dong*, Xiaoming Hao, Daman Singh Pokhrel, Xiaoling Chen, Xiaoguang Liu, Nokuthula Peace Mchunu, Kugenthiren Permaul, Suren Singh, Dandan Niu, Zhengxiang Wang*. Molecular cloning and biochemical characterization of two novel oligo-1,6-glucosidases from Bacillus mycoides and Thermomyces lanuginosus [J]. Starch - Stärke, 2018, 70(1-2): 1700093.

8、Zixing Dong, Zhixin Chen, Hongbin Wang, Kangming Tian, Peng Jin, Xiaoguang Liu, Nokuthula Peace Mchunu, Kugenthiren Permaul, Suren Singh, Dandan Niu, Zhengxiang Wang*. Tandem mass tag-based quantitative proteomics analyses reveal the response of Bacillus licheniformis to high growth temperatures [J]. Ann Microbiol, 2017, 67(7): 501-510.

9、Zixing Dong, Juan Zhang*, Guocheng Du, Jian Chen, Huazhong Li and Beyonghoon Lee*. Periplasmic export of bile salt hydrolase in Escherichia coli by the twin-arginine signal peptides [J]. Appl Biochem Biotech, 2015, 177(2): 458-471.

10、Zixing Dong, Juan Zhang*, Huazhong Li, Guocheng Du, Jian Chen and Beyonghoon Lee*. Codon and propeptide optimizations to improve the food-grade expression of bile salt hydrolase in Lactococcus lactis [J]. Protein Peptide Lett, 2015, 22(8): 727-735.

11、Zixing Dong, Lei Gu, Juan Zhang*, Miao Wang, Guocheng Du, Jian Chen, Huazhong Li*. Optimisation for high cell density cultivation of Lactobacillus salivarius BBE 09-18 with response surface methodology [J]. Int Dairy J, 2014, 34(2): 230-236.

12、Zixing Dong, Juan Zhang*, Beyonghoon Lee, Huazhong Li, Guocheng Du, Jian Chen*. Secretory expression and characterization of a bile salt hydrolase from Lactobacillus plantarum in Escherichia coli [J]. J Mol Catal B-Enzym, 2013, 93 (0): 57-64.

13、Zixing Dong, Juan Zhang*, Beyonghoon Lee, Huazhong Li, Guocheng Du, Jian Chen*. A bile salt hydrolase gene of Lactobacillus plantarum BBE7 with high cholesterol-removing activity [J]. Eur Food Res Technol, 2012, 235(3): 419-427.

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