Zhang Bing
General Information
Name： Zhang Bing
Gender： Female
Birth: 04/1987
Telephone: 15236029833
Email： 15236029833@163.com
Learning experience
2011-9 to 2015-7, Doctor, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Cell Biology
2008-9 to 2011-7, Master, Henan Agricultural University, Botany
2004-9 to 2008-7, Bachelor, Nanyang Normal University, Biological Sciences,
Work experience
2015.07 to 2020.10 Lecturer at the School of Agricultural Engineering, Nanyang Normal University
2020.10 to 2024.0431 Lecturer at the School of Life Sciences and Agricultural Engineering, Nanyang Normal University
2024.04-till now Lecturer at the School of Life Sciences, Nanyang Normal University
Teaching work
Main courses: Genetics, Botany, Plant Physiology, etc.
Scientific research direction
Research on Cell Cycle Regulation of Silkworms, Mechanisms of Histone Phosphorylation Modification and Protein Kinase Regulation in Cytokinesis, Relationship between Chromatin Mediated Multipole Spindle Assembly and Cell Polyploidization Regulation, How to Regulate Host Cell Cycle Process after Virus Infection, Screening of Effective Targets for Biopesticides, and Bacterial Mediated dsRNA Synthesis。
Scientific research achievements
research project
1. Henan Provincial Department of Science and Technology, Science and Technology Research and Development，232102310396，Research on the production of HPV multivalent VLP vaccine using silkworm bioreactor，2022-01 to 2024-12, Guiding project proposal, ongoing research, and hosting；
2. Henan Provincial Department of Education, Key Project，22A180007，Study on the chromatin mediated spindle assembly mechanism of BmN4 cells in the early and middle stages of mitosis regulated by Haspin gene，2022-01 to 2023-12，50000 RMB，Completed, host；
3. Henan Provincial Department of Education, Key Project，17A180009，Study on the Mechanism of Haspin Gene Regulating the Mitotic Cycle of Silkworms，2017-01 to 2020-12，50000 RMB，Completed, host；
4. Nanyang Normal University, School level Youth Fund Cultivation Project，218268，Molecular Mechanism of Haspin Gene Regulating sisters Chromosome Orientation and Separation in Maize Meiosis，2021-01 to 2023-12，30000RMB，Completed, host；
5. Nanyang Normal University, school level project，16101，Molecular mechanism of chromosome orientation and segregation in silkworms，2016-01 to 2020-12，150000RMB，Completed, host；
6. National Natural Science Foundation of China, General Project，31970480, Research on the regulation of sex determination and alternative splicing mechanism of key genes in fruit flies by nucleolar small RNAs，2020-01 to 2023-12，580000RMB，Completed, participate in。
Selected Publication
1. Zhang Bing*§, Camilo Ayra-Pardo§, Liu Xiao-ning, Song Mei-ting, Li Dan-dan, Kan Yun-Chao*, siRNA-Mediated BmAurora B Depletion Impedes the Formation of Holocentric Square Spindles in Silkworm Metaphase BmN4 Cells. Insects. 2024, 15, 72:1-12. DOI: 10.3390/insects15010072
2. Zhang Bing, Wang Yi, Li Na, Li Dan-dan, Kan Yun-chao。Functional analysis of survivin gene in the mitosis of BmN4 cells of Bombyx mori, Kun Chong Xue Bao, 2022, 65(5): 541-547。
3. Zhang Bing, Li Na, Kan Yun-chao, Comparative microRNA microarray and transcriptome analyses of the testis and ovary of the 5th instar larvae of the silkworm, Bombyx mori, Kun Chong Xue Bao, 2021, 64(11): 1235-1243。
4. 张冰, Xu Qian, Tang Cunduo, Wang Jiaoling, Wu Panpan, Zhu Lulu, Kan Yun-chao。Dynamic localization of histone H3 Thr3 phosphorylation in Sf9 cells during mitosis, Kun Chong Xue Bao, 2018, (11): 1247-1252。
5. Zhang Bing§, Lv Zhen-ling§, Pang Jun-ling§, Liu Ya-lin, Guo Xiang, Fu Shu-lan, Li Jun, Dong Qian-hua, Wu Hua-Jun, Gao Zhi, Wang Xiu-Jie, Han Fang-pu. Formation of a functional maize centromere after loss of centromeric sequences and gain of ectopic sequences., Plant Cell, 2013, 25(6): 1979-1989. DOI: 10.1105/tpc.113.110015
6. Zhang Bing, Dong Qianhua, Su Handong, Birchler James A, Han Fangpu. Histone phosphorylation: its role during cell cycle and centromere identity in plants., Cytogenetic and genome research, 2014, 143, 144-149. DOI: 10.1159/000360435
7. Fu Shulan, Lv Zhenling, Gao Zhi, Wu Huajun, Pang Junling, Zhang Bing, Dong Qianhua, Guo Xiang, Wang Xiujie., Birchler JamesA, Han Fangpu. De novo centromere formation on a chromosome fragment in maize. Proceedings of the National Academy of Sciences of the United States of America 2013, 110, 6033-6036. DOI: 10.1007/s10577-021-09670-5