Name: Yuping Wei
Sex: Male
Title: Associate Professor
E-mail: fuziannwei@163.com
1. EDUCATION
2010/09-2014/12, University of Chinese Academy of Sciences, Biological and Chemical Engineering, Ph.D.
2007/09-2009/06, Tianjin University, Biological and Chemical Engineering, Master.
2003/09-2007/06, East China University of Science and Technology, Bioengineering, Bachelor.
2. PROFESSIONAL EXPERIENCE
2018.05-present, College of Life Sciences, Nanyang Normal University, Lecturer, Associate Professor.
2015/02-2017/09, Institute of Process Engineering, Chinese Academy of Sciences, Assistant Researcher.
3. COURSES
(1) For undergraduate courses: hosted the elite online open course of Henan Province, first-class course of Henan Province "Cell engineering".
(2) For graduate courses: hosted the graduate elite online open course of Henan Province "biological reaction engineering and reactor".
4. RESEARCH
Research field: Drug delivery, functional peptide design and molecular simulation.
Presided one National Natural Science Foundation Youth project and two Henan Province science and technology research projects, participated in one National Natural Science Foundation major research project and five other National Natural Science Foundation projects; He has published nearly 20 SCI papers and granted 11 patents.
5. REPRESENTATIVE PUBLICATIONS
(1) Yuping Wei; Ziyang Liu; Man Zhang; Xingyan Zhu; Qionghong Niu; Inhibition of ACE2–S Protein Interaction by a Short Functional Peptide with a Boomerang Structure,Molecules,2024, 29(13): 3022-3024
(2) Yuping Wei; Man Zhang; Pengfei Jiao; Xin Zhang; Ganggang Yang; Xia Xu ; Intracellular Paclitaxel Delivery Facilitated by a Dual-Functional CPP with a Hydrophobic Hairpin Tail, ACS Applie d Materials & Interfaces, 2021, 13(4): 4853-4860
(3) Yuping Wei; Caiying Zhang; Man Zhang; Qionghong Niu; Fengli Hui; Zi Liu; Xia Xu ; Insight of Synergistic Effect between CPP and Cargo on the Facilitation Mechanisms of R7-PTX Translocatio n: Experiments and Molecular Simulations, European Journal of Pharmaceutical Sciences, 2021, 161(1): 105790-105798
(4) Yuping Wei; Liang Zhang; Yankai Fu; Xia Xu ; Rapid delivery of paclitaxel with an organic solvent-free system based on a novel cell penetrating peptide for suppression of tumor growth, Jo urnal of Materials Chemistry B, 2017, 5: 7768-7774
(5) Yuping Wei; Liang Ma; Liang Zhang; Xia Xu ; Non-covalent Interaction Assisted Drug Delive ry System with Highly Efficient Uptake and Release of Paclitaxel for Anticancer Therapy, Internat ional Journal of Nanomedicine, 2017, 12: 7039-7051
(6) Yuping Wei; Chunlong Li; Liang Zhang; Xia Xu ; Design of novel cell penetrating peptides for the delivery of trehalose into mammalian cells, Biochimica et Biophysica Acta (BBA) - Biomemb ranes, 2014, 1838(7): 1911-1920