姓名:冀君
性 别:男
学 位:博士
专 业:动物病毒学与免疫学
职 称:副教授
所在系别:生命科学与农业工程学院
电子邮箱:jijun84@qq.com
一、个人简介
主要研究领域为微生物致病机理,生物制品研发等基础与应用研究。近年来,共以第一作者发表SCI论文近20篇,主持国家级项目 1项,科技厅项目2项;获得省科技进步奖三等奖1项;获得横向项目3项;总到账经费57万元。近五年以第一作者或通讯作者发表SCI论文20篇(中科院一区3篇,二区9篇,三区6篇,四区2篇),一级学报2篇,授权实用新型专利2项,申报发明专利6项,实审6项。
二、主要学术成就:
1.国际首次鉴定并报道了多种动物病毒,并探讨了宽宿主谱病毒的跨宿主传播模式。
2.国际首次建立了多种病原的新型诊断方法。
三、主持或参加的研究项目:
1. gga-miR-221/222-ERK/NF-kB信号轴促进J亚群禽白血病病毒致瘤作用的分子机制,国家自然科学基金项目,31802185、2019/01-2021/12、24万、主持,在研;
2. 基于脆性基因启动子甲基化大肠癌早期诊断筛查试剂盒,河南省科技厅产学研项目,2018/01-2019/12、5万、主持,在研;
3. 识别配体穿膜肽共修饰凋亡素抗肿瘤研究、河南省国际合作项目,152102410055、2015/01-2017/08、10万、主持,已结题;
4. 南阳天华制药集团横向合作项目,16813、广谱多亚型禽流感卵黄抗体的研制、2016/12-2017/12、8万、主持,已结题;
5. 南阳大尧生物科技有限公司横向合作项目,16812、基于脆性基因启动子甲基化大肠癌早期诊断筛查试剂盒、2016/11-2017/11、5万、主持,已结题;
6. 广州云索生物科技有限公司横向合作项目,17809、禽源病毒高效繁殖细胞载体的筛选、2017/09-2019/09、10万、主持,已结题;
7. 南阳师范学院高层次人才科研启动费资助项目,70638、鸡传染性贫血病毒新型繁殖细胞载体的构建与筛选、2014/01-2016/12、10万、主持,已结题。
四、代表性研究成果、授权专利和学术奖励情况:
科研奖励:
1. 水禽常发病防控技术体系的建立与应用;广东省科学技术奖,三等奖,2016.02,广东省人民政府
代表论著:
1.Qinxi Chen, Zhengli Yu, Xin Xu, Jun Ji* et al. First report of a novel goose astrovirus outbreak in Muscovy ducklings in China. Poultry Science. 2020. (中科院二区,影响因子:3.351;通讯作者)
2. Jun Ji#,*, Qinxi Chen, Chaoge Sui et al. Novel Genotype Definition and Genome Characteristics of Duck Circovirus in Central and Eastern China. Transboundary and Emerging Diseases. 2020. (中科院一区,影响因子:5.016;通讯作者)
3. Jun Ji#,*, Qinxi Chen, Chaoge Sui et al. Rapid and visual detection of novel astroviruses causing fatal gout in goslings using one-step reverse transcription loop-mediated isothermal amplification. Poultry Science. 2020. (中科院二区,影响因子:3.351;第一作者,通讯作者)
4. Jun Ji#,*, Yuyun Gao, Qinxi Chen et al. Epidemiological Investigation of Avian Infectious Bronchitis and Locally Determined Genotype Diversity in Central China: A 2016-2018 Study. Poultry Science. 2020. (中科院二区,影响因子:3.351;第一作者,通讯作者)
5. Qinxi Chen, Xin Xu, Zhengli Yu, Chaoge Sui, Kejing Zuo, Guanglin Zhi, Jun Ji* et al. Characterization and Genomic Analysis of Emerging Astroviruses Causing Fatal Gout in Goslings. Transboundary and Emerging Diseases. 2020. (中科院一区,影响因子:5.016;通讯作者)
6. Jun Ji#,*, Wen Hu, Qiang Liu et al. Genetic Analysis of Cachavirus- Related Parvoviruses Detected in Pet Cats: the First Report from China. Frontiers in veterinary science. 2020. (中科院二区,影响因子:3.342;第一作者,通讯作者)
7. Jun Ji#,*, Qinxi Chen, Zhengli Yu, Simple and Visible Detection of Novel Astroviruses Causing Fatal Gout in Goslings Using One-Step Reverse Transcription Polymerase Spiral Reaction Method. Frontiers in veterinary science. 2020. (中科院二区,影响因子:3.342;第一作者,通讯作者)
8. Wen Hu, Liangyan Zheng, Xin Xu, Qiang Liu, Jun Ji* et al. Genetic characterisation and local genotypes of canine parvovirus strains collected from pet dogs in central and eastern China during 2018–2019. Journal of Veterinary Research. 2020. (中科院四区,影响因子:1.742;通讯作者)
9. Wen Hu, Xin Xu, Qiang Liu, Jun Ji* et al. Molecular Characterisation and Genetic Diversity of Canine Parvovirus Type 2 Prevalent in Central China. Journal of Veterinary Research. 2020. (中科院四区,影响因子:1.742;通讯作者)
10. Wen Hu, Qiang Liu, Qinxi Chen, Jun Ji*. Molecular characterization of Cachavirus firstly detected in dogs in China. Infect Genet Evol. 2020. (中科院三区,影响因子:3.342;通讯作者)
11. Xin Xu, Xueyu Wang, Wen Hu, Jun Ji*. An Improved Polymerase Cross-Linking Spiral Reaction Assay for Rapid Diagnostic of Canine Parvovirus 2 Infection. Frontiers in veterinary science. 2020. (中科院二区,影响因子:3.342;通讯作者)
12. Jun Ji#,*, Wanyu Li, Wen Hu er al. Novel Genotype Definition and the First Epidemiological Investigation of Canine Adenovirus Type 2 in Dogs in Central China. Frontiers in veterinary science. 2020. (中科院二区,影响因子:3.342;第一作者,通讯作者)
13. Jun Ji#,*, Xin Xu, et al. Simple and visible detection of duck hepatitis B virus in ducks and geese using loop-mediated isothermal amplification. Poultry Science. 2020. (中科院二区,影响因子:3.351;第一作者,通讯作者)
14. Qianqian Wu, Xin Xu, Jun Ji* et al. Rapid and visible detection of Mycoplasma synoviae using a novel polymerase spiral reaction assay. Poultry Science. 2019. (中科院二区,影响因子:3.351;通讯作者)
15. Qianqian Wu, Xin Xu, Qinxi Chen, Jun Ji*, et al. Genetic Analysis of Avian Gyrovirus 2 Variant-Related Gyrovirus Detected in Farmed King Ratsnake ( Elaphe carinata): The First Report From China. Pathogens. 2019. (中科院三区,影响因子:3.405;通讯作者)
16. Jun Ji#,*, Xin Xu, et al. First Report of Colletotrichum siamense Causing Leaf Spot on Redbud in China. Plant Disease. 2019. (中科院一区,影响因子:3.583;第一作者通讯作者)
17. Jun Ji#,*, Xin Xu, et al. Novel polymerase spiral reaction assay for the visible molecular detection of porcine circovirus type 3. BMC Veterinary Research. 2019. (中科院三区,影响因子:1.792;第一作者通讯作者)
18. Xueyu Wang, Xin Xu, Jun Ji* et al. Visual detection of porcine epidemic diarrhea virus using a novel reverse transcription polymerase spiral reaction method. BMC Veterinary Research. 2019. (中科院三区,影响因子:1.792;通讯作者)
19. Jun Ji#,*, Xin Xu, et al. Expression of dysregulated miRNA in vivo in DF-1 cells during the course of subgroup J avian leukosis virus infection. Microbial Pathogenesis. 2019. (中科院三区,影响因子:2.914;第一作者,通讯作者)
20. Ji Jun#,*, Shang Huiqin, et al. Temporal changes of microRNA gga-let-7b and gga-let-7i expression in chickens challenged with subgroup J avian leukosis virus. Veterinary Research Communications. 2017. (中科院三区,影响因子:1.696;第一作者,通讯作者)
? 21. 冀君#,*, 朱晨晨,许鑫,刘晓,冷超粮,史鸿飞,姚伦广,阚云超. 鸡贫血病毒凋亡素基因的可溶性融合表达及抗肿瘤活性分析. 中国生物工程杂志. 2017. (国内一级学报,第一作者,通讯作者)
? 22. Gao Yuyun, Jin Ling, Ji Jun#, et al. Xanthophyll supplementation reduced inflammatory mediators and apoptosis in hens and chicks. Journal of Animal Science. 2016. (中科院二区,影响因子:1.863;并列第一作者)
? 23. Yuyun Gao, Jun Ji#, Ling Jin, et al. Xanthophyll supplementation regulates carotenoid and retinoid metabolism in hens and chicks. Poultry Science. 2016. (中科院二区,影响因子:1.908;并列第一作者)
? 24. Zhenkai Dai, Jun Ji#, Yiming Yan, et al. Role of gga-miR-221 and gga-miR-222 during Tumour Formation in Chickens Infected by Subgroup J Avian Leukosis Virus. Viruses. 2015. (中科院三区,影响因子:3.465;并列第一作者)
? 25. Jun Ji#, Hongxin Li, Huanmin Zhang, et al. Complete Genome Sequence of an Avian Leukosis Virus Isolate Associated with Hemangioma and Myeloid Leukosis in Egg-Type and Meat-Type Chickens. Journal of Virology. 2012.(中科院二区,影响因子:4.663;第一作者)
? 26. Hongmei Li, Jun Ji#, Qingmei Xie, et al. Aberrant expression of liver microRNA in chickens infected with subgroup J avian leukosis virus. Virus Research. 2012.(中科院三区,影响因子:2.941;并列第一作者)
? 27. Qingmei Xie, Jun Ji#, Jingwei Xie, et al. Epidemiology and immunoprotection of nephropathogenic avian infectious bronchitis virus in southern China. Virology Journal. 2011. (中科院三区,影响因子:2.35;并列第一作者)
? 28. Jun Ji#, Jingwei Xie, Feng Chen, et al. Phylogenetic distribution and predominant genotype of the avian infectious bronchitis virus in China during 2008-2009. Virology Journal. 2011. (中科院三区,影响因子:2.35;第一作者)
? 29. Yizhi Liu, Jun Ji#, Qingmei Xie, et al. Isolation and complete genomic characterization of H1N1 subtype swine influenza viruses in southern China through the 2009 pandemic. Virology Journal. 2011. (中科院三区,影响因子:2.35;并列第一作者)
? 30. Zhiqiang Wu, Jun Ji#, Kejing Zuo, et al. Cloning and Phylogenetic Analysis of Hemagglutinin Gene of H9 Subtype Avian Influenza Virus from Different Isolates in China during 2002–2009. Poultry Science. 2010. (中科院二区,影响因子:1.908;并列第一作者)
? 31. Jun Ji#, Qingmei Xie, Cuiying Chen, et al. Molecular Detection of Muscovy duck Parvovirus by Loop-mediated Isothermal Amplification Assay. Poultry Science. 2010. (中科院二区,影响因子:1.908;第一作者)
? 32. Qing-mei Xie, Jun Ji#, Tristan Tyler Pickens, et al. Rapid Detection of Infectious Laryngotracheitis Virus Isolates by Loop-mediated Isothermal Amplification. Journal of Virological Methods. 2010. (中科院四区,影响因子:2.011;并列第一作者)
? 33. Qingmei Xie, Jun Ji#, Liqin Du, et al. Preparation and immune activity analysis of H5N1 subtype avian influenza virus recombinant protein-based vaccine. Poultry Science. 2009. (中科院二区,影响因子:1.908;并列第一作者)
? 34. Jun Ji#, Liqin Du, Qingmei Xie, et al. Rapid diagnosis of duck plagues virus infection by loop-mediated isothermal amplification. Research in Veterinary Science. 2009. (中科院三区,影响因子:1.649;第一作者)
? 35. 冀君#,陈燕珊,张祥斌,陈俊伟,马静云,毕英佐,谢青梅. 广西黄鸡β-防御素基因的克隆、序列分析与组织分布. 华南农业大学学报. 2008. (国内二级学报)