博士

Email：wenchaogao@whu.edu.cn

基本信息

主要研究方向为有机电化学在药物小分子中的应用研究；手性配体设计合成及在不对称氢化中的应用。发表SCI学术论文8篇，其中一区和二区论文7篇。承担课程：药物合成、天然药物化学、制药工程专业实验等。

教育经历

2014-2017 武汉大学化学与分子科学学院有机化学专业 博士

2011-2014 郑州大学化学与分子工程学院有机化学专业 理学硕士

2007-2011 郑州大学化学系理学学士

工作履历

2018-至今化学与制药工程学院 讲师

2017-2018武汉药明康德新药开发有限公司 高级研究员

研究方向

有机电化学在药物小分子中的应用研究；

手性配体设计合成及在不对称氢化中的应用

学术成果

代表性论文（限10篇）：

1. Wenchao Gao* (第一作者), Beibei Li, Luyi Zong, Lintao Yu, Xuyang Li, Qiyang Li, Xu Zhang, Sheng Zhang* and Kun Xu*, Electrochemical Tandem Cyclization of Unsaturated Oximes with Diselenides: A General Approach to Seleno Isoxazoines Derivatives with Quaternary Carbon Center, Eur. J. Org. Chem. 2021, 2021(17), 2431-2435.

2. Sheng Zhang* (第一作者), Lijun Li, Jingjing Li, Jianxue Shi, Kun Xu*, Wenchao Gao, Luyi Zong, Guigen Li and Michael Findlater*, Electrochemical Arylation of Aldehydes, Ketones, and Alcohols: From Cathodic Reduction to Convergent Paired Electrolysis, Angew. Chem. Int. Ed. 2021, 60(13), 7275-7282.

3. Shanshan Liu, Wenchao Gao, Yuhang Miao, Mincan Wang(*), Dinuclear zinc-azePhenol catalyzed asymmetric aza-Henry reaction of N-Boc imines and nitroalkanes under ambient conditions. J. Org. Chem. 2019, 84, 2652-2659.

4. Jiao Long, Wenchao Gao, Yuqing Guan, Hui Lv(*), Xumu Zhang(*), Nickel-catalyzed highly enantioselective hydrogenation of β-acetylamino vinylsulfones: access to chiral β-amido sulfones. Org. Lett. 2018, 20, 5914-5917.

5. Wenchao Gao, Hui Lv(*), Tonghuan Zhang, Yuhong Yang, Lung Wa Chung(*), Yun-Dong Wu and Xumu Zhang(*), Nickel-catalyzed asymmetric hydrogenation of β-acylamino nitroolefins: an efficient approach to chiral amines. Chem. Sci. 2017, 8, 6419-6422.

6. Wenchao Gao, Hui Lv(*), Xumu Zhang(*), Rh/DuanPhos-Catalyzed Asymmetric Hydrogenation of β-Acetylamino Vinylsulfides: An Approach to Chiral β-Acetylamino Sulfides. Org. Lett. 2017, 19, 2877-2880.

7. Wenchao Gao(#), Qingli Wang(#), Yun Xie, Hui Lv(*), Xumu Zhang(*), Rhodium-catalyzed Asymmetric Hydrogenation of α-Dehydroamino Ketones: A General Approach to Chiral α-amino Ketones. Chemistry - An Asian Journal, 2016, 11，231-233.

8. Qingli Wang(#), Wenchao Gao(#), Hui Lv(*), Xumu Zhang(*), Enantioselective synthesis of β-substituted Chiral Allylic Amines via Rh-Catalyzed Asymmetric Hydrogenation. Chem. Commun. 2016, 52, 11850-11853.