董自星，1986年生，男，博士，讲师。毕业于江南大学，主要从事工业酶制剂的基因挖掘、分子改造、高效表达和应用等方面的研究工作。
目前主持南阳师范学院校级博士专项项目1项，参与省部级以上项目5项以及横向项目2项。共发表学术论文40余篇，其中以第一作者身份发表SCI论文12篇，累计影响因子接近30。授权中国发明专利4项。
大学开始受教育经历
2004.09-2008.07 东北农业大学    生命科学学院     本科
2008.09-2014.01 江南大学        生物工程学院     博士
工作经历
2019.04-现在   南阳师范学院中英联合实验室   讲师
2015.06-2019.03 天津科技大学化工与材料学院   助理研究员
2014.11-2015.05 天津科技大学生物工程学院   助理研究员
主持的科研项目
1. 南阳师范学院校级博士专项：适用于淀粉糖化过程的耐酸耐热异淀粉酶的构建及高效表达，主持，在研
2. 国家重点研发计划项目：农业生物质综合生物加工用酶库. 酶复配技术与新菌种（YS2018YFGH000002），参与，在研
3. 国家自然科学基金面上项目：基于末端组学深度解析食品碱性蛋白酶的动态水解规律及其位点选择特性（31871740），参与，在研
4. 国家自然科学基金面上项目：维生素D3前体生物合成关键酶胆固醇7-脱氢酶系的构效研究（31771911），参与，在研
5. 天津市高等学校创新团队建设计划：酶与生物催化关键技术（TD12-5002），参与，已结题
6. 天津市科委人才引进与科技合作项目：耐热脂肪酶产生菌的筛选及其发酵优化研究（14RCGHSY00181），参与，已结题
代表性论文
1. Zixing Dong*, Shuangshuang Yang, Byonghoon Lee. Bioinformatic mapping of a more precise Aspergillus niger degradome [J]. Sci Rep-UK, 2021, 11(1): 693.
2. Zixing Dong*, Cunduo Tang, Yunfeng Lu, Lunguang Yao, Yunchao Kan. Microbial oligo-α-1,6-glucosidase: Current developments and future perspectives [J]. Starch - Stärke, 2020, 72(1-2): 1900172.
3. Zixing Dong*, Xiaoling Chen, Ke Cai, Peili Shen, Kangming Tian, Peng Jin, Xiaoguang Liu, Zhengxiang Wang*. Overexpression of the Bacillus licheniformis GroES enhances thermotolerance of Bacillus subtilis WB600 [J]. Biotechnol Biotec Eq, 2018, 32 (6): 1527-1532.
4. Zixing Dong*, Beyonghoon Lee. Bile salt hydrolases: Structure and function, substrate preference and inhibitor development [J]. Protein Sci, 2018, 27: 1742-1754.
5. Zixing Dong, Xiaoling Chen, Ke Cai, Zhixin Chen, Hongbin Wang, Peng Jin, Xiaoguang Liu, Kugenthiren Permaul, Suren Singh, Zhengxiang Wang*. Exploring the metabolic responses of Bacillus licheniformis to temperature stress by gas chromatography/mass spectrometry [J]. J Microbiol Biotechnol, 2018, 28(3): 473-481.
6. Haiyang Wu, Xiaojing Tian, Zixing Dong*, Yongjie Zhang, Lei Huang, Xiaoguang Liu, Peng Jin, Fuping Lu, Zhengxiang Wang*. Engineering of Bacillus amyloliquefaciens α-amylase with improved calcium independence and catalytic efficiency by error-prone PCR [J]. Starch - Stärke, 2018, 70(3-4): 1700175.
7. Zixing Dong*, Xiaoming Hao, Daman Singh Pokhrel, Xiaoling Chen, Xiaoguang Liu, Nokuthula Peace Mchunu, Kugenthiren Permaul, Suren Singh, Dandan Niu, Zhengxiang Wang*. Molecular cloning and biochemical characterization of two novel oligo-1,6-glucosidases from Bacillus mycoides and Thermomyces lanuginosus [J]. Starch - Stärke, 2018, 70(1-2): 1700093.
8. Zixing Dong, Zhixin Chen, Hongbin Wang, Kangming Tian, Peng Jin, Xiaoguang Liu, Nokuthula Peace Mchunu, Kugenthiren Permaul, Suren Singh, Dandan Niu, Zhengxiang Wang*. Tandem mass tag-based quantitative proteomics analyses reveal the response of Bacillus licheniformis to high growth temperatures [J]. Ann Microbiol, 2017, 67(7): 501-510.
9. Zixing Dong, Juan Zhang*, Guocheng Du, Jian Chen, Huazhong Li and Beyonghoon Lee*. Periplasmic export of bile salt hydrolase in Escherichia coli by the twin-arginine signal peptides [J]. Appl Biochem Biotech, 2015, 177(2): 458-471.
10. Zixing Dong, Juan Zhang*, Huazhong Li, Guocheng Du, Jian Chen and Beyonghoon Lee*. Codon and propeptide optimizations to improve the food-grade expression of bile salt hydrolase in Lactococcus lactis [J]. Protein Peptide Lett, 2015, 22(8): 727-735.
11. Zixing Dong, Lei Gu, Juan Zhang*, Miao Wang, Guocheng Du, Jian Chen, Huazhong Li*. Optimisation for high cell density cultivation of Lactobacillus salivarius BBE 09-18 with response surface methodology [J]. Int Dairy J, 2014, 34(2): 230-236.
12. Zixing Dong, Juan Zhang*, Beyonghoon Lee, Huazhong Li, Guocheng Du, Jian Chen*. Secretory expression and characterization of a bile salt hydrolase from Lactobacillus plantarum in Escherichia coli [J]. J Mol Catal B-Enzym, 2013, 93 (0): 57-64.
13. Zixing Dong, Juan Zhang*, Beyonghoon Lee, Huazhong Li, Guocheng Du, Jian Chen*. A bile salt hydrolase gene of Lactobacillus plantarum BBE7 with high cholesterol-removing activity [J]. Eur Food Res Technol, 2012, 235(3): 419-427